Products | ViiV Healthcare

By: Viiv Healthcare  09-12-2011
Keywords: Hiv, medicines, Protease Inhibitor

HIV medicines belong to the class of antiretroviral drugs, often known as ARVs. These drugs reduce the amount of HIV in the body and so help a person to remain healthy for longer. There are several types of ARV and each type inhibits HIV in a different way. Some ARVs stop the virus entering cells of the body; other ARVs stop the HIV replicating inside human cells if it gets in.

The five main types of antiretroviral medicine are:

  • Nucleoside reverse transcriptase inhibitors (NRTIs) and nucleotide reverse transcriptase inhibitors (N(t)RTIs), stop HIV replicating by blocking the viral enzyme reverse transcriptase
  • Non-nucleoside reverse transcriptase inhibitors (NNRTIs) also block reverse transcriptase but in a different way to NRTIs
  • Protease inhibitors (PIs), which prevent the production of mature, infectious virus particles in infected human cells by blocking an enzyme called protease
  • Fusion or Entry Inhibitors, which stop HIV from entering human cells where they could replicate
  • Integrase inhibitors, stop HIV replicating in cells by blocking a viral enzyme called integrase

A combination of these medicines is usually recommended and is known as HAART or highly active antiretroviral therapy. HAART has significantly improved life expectancy.

Product brand name (generic name) Class
Combivir (lamivudine + zidovudine) NRTI
Epivir (lamivudine, also known as 3TC) NRTI
Epzicom*/Kivexa (abacavir + lamivudine) NRTI
Lexiva*/Telzir (fosamprenavir) Protease inhibitor
Rescriptor (delavirdine) NNRTI (US only)
Retrovir (zidovudine, also known as AZT) NRTI
Selzentry*/Celsentri (maraviroc) Entry inhibitor (CCR5 antagonist)
Trizivir (abacavir + lamivudine + zidovudine) NRTI
Viracept (nelfinavir) Protease inhibitor
(N. America only)
Ziagen (abacavir) NRTI

*US only brand name

Find out more about our medicines through the links below:

Keywords: Entry Inhibitor, Entry Inhibitors, Hiv, Hiv Medicines, medicines, Nrti, Protease Inhibitor, Protease Inhibitors,