Luminex 100/200 Overview
The Luminex 100/200 System is a flexible analyzer based on the principles of flow cytometry. The system enables you to multiplex (simultaneously measure) up to 100 analytes in a single microplate well, using very small sample volumes. The system delivers fast and cost-effective bioassay results on many assay formats including nucleic acid assays, receptor-ligand assays, immunoassays and enzymatic assays.
The Luminex 100/200 System is the combination of three core xMAP Technologies. The first is , a family of 100 fluorescently dyed 5.6 micron-sized polystyrene microspheres that act as both the identifier and the solid surface to build the assay. The second is a flow cytometry-based instrument, the Luminex 100/200 analyzer, which integrates key xMAP detection components such as lasers, optics, fluidics and high-speed digital signal processors. The third component is the , which is designed for protocol-based data acquisition with robust data regression analysis.
The Luminex 100/200 is a class 1(I) laser product.
xPONENT® Software Solutions
Data Acquisition and Analysis for Luminex Instrumentation
is a modular, flexible, software package for control of the , Luminex 100/200 and . The software’s graphical user interface follows the typical assay workflow but can be customized to meet the needs of a specific laboratory.
xPONENT software is available with three levels of accessibility.
The basic xPONENT software package allows the user to acquire samples, perform analysis, and run system maintenance routines and remote web monitoring. This package includes the ability to calculate allelic ratios to analyze and/or normalize genotyping data.
The secure xPONENT package includes all the basic functionality, plus allows an administrator to set up user access levels.
21 CFR Part 11
For laboratories working under the FDA’s 21 CFR Part 11 regulations, xPONENT offers multilevel user management, full audit trail, electronic records and electronic signatures.
In addition to the access levels listed above, there are two additional licensable modules that add specific functions:
The automation module along with a device driver enables communication between the reader and a front end automation platform. Luminex device drivers are offered by many automation providers. For more information on available drivers please contact Luminex Technical Support.
This module allows communication with an external Laboratory Information System (LIS) database by allowing the export of patient result data and the import of patient sample information in ASTM format. Connection to your LIS system may require the use of middleware. For more information on middleware solutions please contact Luminex Technical Support.