Non-Invasive Prenatal DNA Gender test on Maternal Blood

By: Health Genetic Center  09-12-2011
Keywords: Blood Samples, Prenatal Diagnosis, Gender Test,

The current available techniques for prenatal diagnosis (CVS and amniocentesis) are invasive and carry with their use a small but significant chance of miscarriage. As a result, the current standard care offers an invasive prenatal gender test only to those women whose risk of chromosomal or genetic abnormalities are greater than or equal to the risk of a procedure-related loss. This means that the vast majority of women never receive the benefits of a gender test prediction. The recent discovery of the presence of fetal genetic material in maternal blood has offered new approaches to non-invasive prenatal diagnosis. The concentration of fetal DNA in maternal blood was found to be much higher than that present in the cellular fraction. Given the relatively easy identification of male DNA in maternal blood, one clinical application is the non-invasive identification of male fetuses at risk for X-linked disorders. The second is a curiosity application for the parents who would like to know the gender of the baby. This webpage explains in details how and when you can do the non-invasive prenatal gender test.

Advantages of fetal DNA analysis in maternal blood

1. Analysis of fetal DNA and fetal cells in maternal blood samples is a screening test that is a non-invasive prenatal procedure and poses no risks to the mother or the fetus. The non-invasive baby gender predictor is based on the detection of Y chromosome-specific DNA in maternal blood samples.

2. This DNA identity baby gender test is relatively inexpensive in comparison to invasive techniques such as CVS or amniocentesis.

Timing for the test

Using DNA test from Health Genetic Center, a gender confirmation (Y-chromosome detection) can be done at 10 weeks of gestation.

Results

The procedure takes 7 business days, and the final report contains one of the following results:

- POSITIVE for the presence of Y-chromosome. Positive Y chromosome DNA test confirms the presence of a male fetus in the recent pregnancy.

- NEGATIVE for the presence of Y-chromosome. Negative DNA test result confirms the absence of Y chromosome DNA in maternal blood samples. This means that 1) the mother is carrying a female fetus or 2) amount of fetal DNA in maternal blood is very low (lower than the detection limit of the DNA test). Please note that if the sample is collected after 10 weeks of pregnancy then the technique is sensitive enough to detect a small amount of fetal DNA in mother’s blood. Only in very rare cases (less than 1%) this amount lower is than the detection limit at 10 weeks of pregnancy.

Sensitivity and specificity of the test

Sensitivity and specificity of the detection of male fetuses at 10 weeks of gestation for properly collected maternal blood samples is more than 99%.

Price for the Prenatal Gender Test

Total price of laboratory DNA testing for baby gender test determination is $390.00 (US). The cost includes the diagnostic laboratory test, telephone consultations, sample collection kit, and final laboratory report. Please make sure the payment for the DNA baby gender test is included in the form of money order, VISA, Master Card or American Express. A non-refundable deposit of $100.00 is required to initiate the scheduling process and will be applied towards the case. The balance must be paid in full before we can release the DNA gender test results. All prices are in US dollars.

The information in this article was current at 06 Dec 2011

Keywords: Blood Samples, Gender Test, Prenatal Diagnosis,

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Non-Invasive Prenatal Paternity Test on Maternal Blood

The cost includes a sample collection kit, the diagnostic laboratory tests for the mother and all alleged fathers, the laboratory reports a) for fetal DNA testing as well as b) free follow-up testing for a newborn child. The Alleged Father cannot be excluded as the biological father of the fetus based on the samples submitted from the mother and the alleged father and the DNA extracted from the population of fetal cells.