PEGylated Glycosides

By: Sussex Research Laboratories  09-12-2011

Sussex PEGylated Glycosides may also be important materials for use as carbohydrate carriers in glycotherapeutic applications, drug carriers for site specific delivery, drug enhancers for decreasing toxicity and solubility and protein enhancers. Virtually any carbohydrate may be carried by PEG.

Sussex Research is a pioneer in the area of PEGylated Glycoside synthesis. PEGylated glycosides are multi-purpose, functionalized products that enable researchers to modify macromolecules, surfaces and nanostructures with carbohydrates via simple polyethylene glycol (PEG) linker systems. PEG linkers are amphiphilic and unlikely to undergo hydrophobic interactions with proteins and other surfaces.

Sussex PEGylated Glycosides may also be important materials for use as carbohydrate carriers in glycotherapeutic applications, drug carriers for site specific delivery, drug enhancers for decreasing toxicity and solubility and protein enhancers. Virtually any carbohydrate may be carried by PEG.


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Other products and services from Sussex Research Laboratories

09-12-2011

Oligosaccharides

In addition to our carbohydrate synthetic experience, the company has an excellent infrastructure including in-house high field nmr and mass spectrometry facilities for structural validation. From blood group to GAG oligosaccharides, we have experience in virtually all aspects of oligosaccharide synthesis. Sussex Research prides itself on its ability to synthesize, purify and fully characterize oligosaccharides.


09-12-2011

Glycoamino Acids

Fmoc Glycoamino Acids enable facile assembly of glycopeptides as well as introduction of carbohydrate-based recognition elements onto a variety of molecules including small molecules and biomolecules such as oligonucleotides and proteins. Sussex Research manufactures the most extensive selection of Glycoamino Acids that are commercially available in the world today.


09-12-2011

Glycopeptides

Synthetic glycopeptides offer a unique frontier for research in glycobiology and proteomics as well as for drug discovery & development, drug delivery/targetting, diagnostics development and biotechnological applications. Carbohydrates on proteins mediate a host of biological events including cell adhesion, immune system function, fertilization, cellular targeting as well as protein transport, stabilization and half-life.


09-12-2011

Products

From functionalized carbohydrate molecules such as Fmoc glycoamino acids for glycopeptide synthesis and PEGylated Glycosides for protein modification to polysaccharides for study and development of vaccines, the Sussex product portfolio is wide-ranging. At Sussex Research, we take great pride in the conception, development and manufacture of a novel portfolio of carbohydrate-based products for the innovative modern researcher.