Glycopeptides

By: Sussex Research Laboratories  09-12-2011

Sussex Research is the leading commercial source of synthetic, well-defined N- and O-linked glycosylated peptides. Synthetic glycopeptides offer a unique frontier for research in glycobiology and proteomics as well as for drug discovery & development, drug delivery/targetting, diagnostics development and biotechnological applications.

The critical role of glycan elements on cell surface proteins and those bound to circulatory proteins is well recognized. Carbohydrates on proteins mediate a host of biological events including cell adhesion, immune system function, fertilization, cellular targeting as well as protein transport, stabilization and half-life. Thus, the use of synthetic glycoproteins or their fragments (glycopeptides) as experimental probes for basic research and biomedical applications is growing rapidly.

Glycopeptides from our Library:

As the leading resource for glycopeptide synthesis, Sussex Research offers a large number of glycopeptides from our inventory.

Custom Glycopeptide Synthesis:

The number and variation of applications of glycopeptides in modern research is impressive. Sussex Research is highly active in the custom synthesis of glycopeptides for specific research, drug and vaccine development projects. You pick the glycoform, the amino acid or linker system, the sequence and the label if necessary…we’ll make it happen.


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Other products and services from Sussex Research Laboratories

09-12-2011

Oligosaccharides

In addition to our carbohydrate synthetic experience, the company has an excellent infrastructure including in-house high field nmr and mass spectrometry facilities for structural validation. From blood group to GAG oligosaccharides, we have experience in virtually all aspects of oligosaccharide synthesis. Sussex Research prides itself on its ability to synthesize, purify and fully characterize oligosaccharides.


09-12-2011

PEGylated Glycosides

Sussex PEGylated Glycosides may also be important materials for use as carbohydrate carriers in glycotherapeutic applications, drug carriers for site specific delivery, drug enhancers for decreasing toxicity and solubility and protein enhancers.


09-12-2011

Glycoamino Acids

Fmoc Glycoamino Acids enable facile assembly of glycopeptides as well as introduction of carbohydrate-based recognition elements onto a variety of molecules including small molecules and biomolecules such as oligonucleotides and proteins. Sussex Research manufactures the most extensive selection of Glycoamino Acids that are commercially available in the world today.


09-12-2011

Products

From functionalized carbohydrate molecules such as Fmoc glycoamino acids for glycopeptide synthesis and PEGylated Glycosides for protein modification to polysaccharides for study and development of vaccines, the Sussex product portfolio is wide-ranging. At Sussex Research, we take great pride in the conception, development and manufacture of a novel portfolio of carbohydrate-based products for the innovative modern researcher.