Easy Vocal Removal
Center panned audio removal usually works well for vocals, bass, and rhythm. However, there are times when center panned audio removal will fail. For these cases, removing non-center panned audio can solve the problem.
Non-Centered Audio Removal
For maximum flexibility, the "Channel Mixer and Advanced Karaoke" mode lets you remove non-center panned audio to filter out instruments that aren't center panned, like lead guitars, with the "Mixer Karaoke" option. This will leave in all centered audio, like vocals or bass guitar, but take out things that the audio engineers panned to the left or right when mixing the recordings.
As with the simple karaoke mode, once the instruments are filtered from the mix, you can then add other instruments back in that were also taken out by adjusting the equalizer for their frequency ranges.