Misonix, Inc. - Hyalomatrix® Advanced Bi-layered Wound Care Device

By: Misonix  09-12-2011
Keywords: Wound Care

Advanced Bi-layered Wound Care Device

3 dimensional HYAFF® (hyaluronic acid ester) matrix

  • allows cellular invasion
  • allows capillary growth
  • positively impacts the natural re-epitheliazation process

Transparent Silicone Membrane

  • protects the lesion / retains the moisture
  • facilitates monitoring with no disruption of the new wound bed

Mechanism of Action

The HYAFF matrix allows cellular invasion by fibroblasts or endothelial cells

  • HYAFF fibers degrade into hyaluronic acid and benzyl alcohol within the wound
  • The presence of hyaluronic acid helps in maintaining well-hydrated tissue and may promote natural re-epithelialization.

Indications For Use

HYALOMATRIX® is indicated for the management of wounds including: partial and full-thickness wounds; second-degree burns; pressure ulcers; venous ulcers; diabetic ulcers; chronic vascular ulcers; tunneled/undetermined wounds; surgical wounds (donor sites/grafts, Post-Moh’s surgery, post-laser surgery, podiatric, wound dehiscence); trauma wounds (abrasions, lacerations, skin tears); and draining wounds. The device is intended for one-time use.

Features and Benefits:

  • Single application device – use for most wounds. Typically one application of Hyalomatrix is required to manage a viable wound bed capable of continuing re-epitheliazation or for the application of a skin graft
  • Avoids some reactions. Hyalomatrix is a hyaluronic acid ester and contains no human or animal products, avoiding porcine and bovine sensitivities
  • Ease of Use – saves time. Hyalomatrix is easy to use: open the sterile pack; quickly identify the HYAFF side that faces the wound; cut the HYAFF pad to size; staple / stitch / tape to the site; 7 days later check the healing progress through the transparent silicone layer on top
  • Pain reduction. Believed to reduce pain by proper coverage of exposed wound tissues. (Caravaggi, et al, Wound Bed Preparation With a Dermal Substitute (Hyalomatrix PA) Facilitates Re-epithelialization and Healing: Results of a Multicenter, Prospective, Observational Study on Complex Chronic Ulcers (The FAST Study), WOUNDS, August, 2011
  • Lower risk of Infection. Cover most wounds / use with or without bacteriocidal dressings
  • Less waste – better inventory control. Hyalomatrix has a 4 year shelf life and can be stored at room temperature, allowing you to keep it on the shelf and have it readily available as needed, with no special handling or storage requirements at a reduced risk of waste.

Brochures and Case Studies


Hyalomatrix is contraindicated for patients with the individual hypersensitivity to hyluronan and/or its derivatives and silicone. Hyalomatrix does not possess bacteriostatic or bactericidal properties and should not be used on infected wounds. Remove Hyalomatrix if wound infection is confirmed. Single use only.

Keywords: Wound Care

Contact Misonix

Email - none provided

Print this page

Other products and services from Misonix


Misonix, Inc. - Lysonix 3000 Ultrasound Assisted Lipoplasty System

When placed in a liquid, the vibrating probe tip causes microscopic bubbles to grow and then collapse with great energy intensity, thus causing the tissue directly in front of the probe to be liquefied or fragment. Cavitation is the formation and collapse of microscopic bubbles which are produced at the tip of the probe that is mounted on the handpiece.


Misonix, Inc. - Advancing Ultrasonic Surgery

The Misonix team specializes in the development, manufacturing, and marketing of advanced ultrasonic devices for soft and hard tissue applications. Our products are optimized for dissection and removal of undesirable tissue while minimizing collateral trauma. Our innovative technologies enable precise surgeries across multiple specialties and surgical applications. Tumor Removal Tissue Debulking Bone Sculpting & Removal.


Misonix, Inc. - SonaStar Ultrasonic Surgical Aspirator System

The Misonix Sonastar™ is an innovation leader in ultrasonic aspiration offering a curved extended plus a compact handpiece, both operating at the powerful 23kHz frequency for quick and efficient removal of hard and calcified tumors. Dynamic tissue management enables intuitive control over loading characteristics from delicate tumor removal over vessel sparing tissue emulsification to debulking of calcified tumors.


Misonix, Inc. - BoneScapel - Ultrasonic Bone Cutting and Shaving System

In combining advantages of both, powered rotary devices and traditional hand instruments, the BoneScalpel offers a new level of precision and safety for cutting bone. The linear motion of a blunt tip avoids accidental trapping of soft tissue matter while eliminating the spinning and tearing associated with rotary power instruments.


Misonix, Inc. - SonicOne Ultrasonic Wound Debridement System

Additionally, the debridement is started proximally to the woundbed surface and advanced distally, which separates infected from viable layers for a more defined treatment and reduced pain sensation. The SonicOne™ offers continuous and pulse modes and a wide range of dedicated ultrasonic tips giving the practitioner a variety of options to adjust the efficacy of the treatment.