SERVICES:Medicinal Chemistry --- TC Scientific Inc. --- Acceleration with our services

By: TC Scientific  09-12-2011
Keywords: scientists, Medicinal Chemistry

Scientists at TC Scientific Inc. are appreciated for their excellent synthetic chemistry talents and knowledge of structure-activity relationships (SAR). They have extensive experience in anticancer, antifungal reagents, antibiotics, central nervous system (CNS), infective disease, and cardiovascular (CV) disease drug discovery. These unique characteristics make it possible for TC Scientific Inc. to deliver solutions and inventions for complex problems and challenging targets in a timely and cost-effective manner. The intellectual property developed is carefully protected, and fully assigned to the client, creating value for the customer.

TC Scientific Inc. provides expert medicinal chemistry support to the biotech and pharmaceutical industries. These services aid a variety of research organizations ranging from start-ups to large companies, as well as government labs and academic groups. We are committed to having close communication with our clients to understand their needs, to establish project objectives, and to adapt and evolve R&D plans in response to experimental results.

We understand that drug discovery is an art as well as a science. We therefore pursue hypothesis-driven strategies while utilizing our creative insights in drug development to drive projects to a meaningful conclusion.

Our scientists work to solve challenging problems culminating in the invention of new drug molecules and, most importantly, the creation of novel intellectual property for our customers.

At TC Scientific Inc., our researchers possess core competencies in aspects of medicinal chemistry, organic synthesis, structure-based drug design, hit-to-lead translation and lead optimization. The dynamic medicinal chemistry team has a wealth of lead discovery and optimization experience in a variety of therapeutic areas. We can design and optimize a narrow set of analogs based on SAR analysis, pharmacophore modeling, safety concerning, chemical purity, in vitro potency, in vivo efficacy, pharmacokinetic and ADME-Toxicity profile. We efficiently and cost-effectively advance our clients' drug discovery projects to the next level.

We deliver efficient and cost effective medicinal chemistry services to clients all over the world. Our approach ensures fast, flexible, client-oriented services, reinforced by strong project management and scientific expertise.

TC Scientific Inc. provides world class chemistry services to its clients as part of a portfolio of high quality, cost-effective and proven drug discovery and development capabilities.

Lead generation and focused library synthesis

Lead optimization

Candidate synthesis route scouting, scale-up and process development

Natural product-like scaffolds, heterocyclic scaffolds, building blocks, reference compounds and impurities synthesis

Keywords: Medicinal Chemistry, scientists

Other products and services from TC Scientific


SERVICES:Custom Synthesis --- TC Scientific Inc. --- Acceleration with our services

We offer custom synthesis of intermediates, novel scaffolds, optically active compounds, active pharmaceutical ingredients, reference compounds and lead compounds to help our clients in their drug discovery and chemical development efforts either on a project basis or under a fixed term contract.


SERVICES:Process Research and Development --- TC Scientific Inc. --- Acceleration with our services

We can work together with our customers' technology groups to assimilate the new process into the manufacturing facility and help customers manufacture their products more efficiently. Our process research and development team is able to develop a safe and economical process that can be utilized on a commercial scale. We can optimize a developed process by using our experience with different equipment, certain raw materials or unit operations.


SERVICES:Scale-Up --- TC Scientific Inc. --- Acceleration with our services

If you do not have a demonstrated route, our extraordinarily talented, creative and experienced scale-up team can develop new and proprietary routes to meet or exceed your expectations. If you already have a demonstrated route and need to reproduce in a timely and cost-effective manner, our scale-up team will meet your expectations. We will identify and develop steps as appropriate for scale or safety considerations.